Browsing by Author "Waelkens, E."
Now showing items 1-3 of 3
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Discovery of a new subclass of alpha-conotoxins in the venom of Conus australis
Lebbe, E.K.M.; Peigneur, S.; Maiti, M.; Mille, B.G.; PrabhaDevi; Ravichandran, S.; Lescrinier, E.; Waelkens, E.; DeSouza, L.; Herdewijn, P.; Tytgat, J. (Elsevier, 2014)Cone snails (Conus sp.) are poisonous animals that can be found in all oceans where they developed a venomous strategy to prey or to defend. The venom of these species contains an undeniable source of unique and potent ... -
Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.
Lebbe, E.; Ghequire, M.; Peigneur, S.; Mille, B.; PrabhaDevi; Ravichandran, S.; Waelkens, E.; DeSouza, L.; DeMot, R.; Tytgat, J. (MDPI AG, Switzerland, 2016)Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds ... -
Structure-function elucidation of a new alpha-Conotoxin, Lo1a, from Conus longurionis.
Lebbe, E.K.M.; Peigneur, S.; Maiti, M.; PrabhaDevi; Ravichandran, S.; Lescrinier, E.; Ulens, C.; Waelkens, E.; DeSouza, L.; Herdewijn, P.; Tytgat, J. (American Society for Biochemistry and Molecular Biology, 2014)Alpha-Conotoxins are peptide toxins found in the venom of marine cone snails and potent antagonists of various subtypes of nicotinic acetylcholine receptors (nAChRs). nAChRs are cholinergic receptors forming ligand-gated ...