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dc.contributor.authorGowda, N.M.
dc.contributor.authorGoswami, U.
dc.contributor.authorKhan, M.I.
dc.date.accessioned2008-11-25T09:26:08Z
dc.date.available2008-11-25T09:26:08Z
dc.date.issued2008
dc.identifier.citationJournal of Invertebrate Pathology, vol.99; 141-145p.
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/1499
dc.description.abstractIn invertebrates, cellular and humoral components are evolved to maintain their body immunity and integrity. Both these factors respond to different antigens such as microorganisms, vertebrate erythrocytes and foreign proteins. In this article, we report a study of a lectin (HSL) involved in immune response in the echinoderm, sea cucumber (Holothuria scabra). Correlative studies indicate that the expression of this defensive lectin is induced by bacterial challenge, wherein cell wall glycoconjugates of bacteria are involved in lectin induction. HSL showed strong broad spectrum antibacterial activity against both grampositive and gram-negative bacteria. Under in vitro conditions, purified HSL mediate agglutination of the test bacteria, there by indicating a possible mode of action in physiological situation.
dc.language.isoen
dc.publisherElsevier
dc.rightsCopyright [2008]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subjectmarine invertebrates
dc.subjectcoelomic fluids
dc.subjectHolothuria scabra
dc.subjectantibiotics
dc.titleT-antigen binding lectin with antibacterial activity from marine invertebrate, sea cucumber (Holothuria scabra): Possible involvement in differential recognition of bacteria
dc.typeJournal Article


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