A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris

dc.contributor.author	Fontana, A.
dc.contributor.author	Cavaliere, P.
dc.contributor.author	Wahidullah, S.
dc.contributor.author	Naik, C.G.
dc.contributor.author	Cimino, G.
dc.date.accessioned	2009-01-09T07:54:11Z
dc.date.available	2009-01-09T07:54:11Z
dc.date.issued	2000
dc.identifier.citation	Tetrahedron, Vol.56; 7305-7308p.
dc.identifier.uri	http://drs.nio.org/drs/handle/2264/1638
dc.description.abstract	A new dimeric isoquinoline alkaloid, jorumycin (3), has been isolated from the skin and the mucus of the Pacific nudibranch Jorunna funebris. The structure has been fully elucidated on the grounds of ESMS data and of an extensive 2D NMR analysis. The cytotoxicity of 3 was evaluated against various human cancer cell lines and was found to be slightly less potent than Et 743 (2)
dc.language.iso	en
dc.publisher	Pergamon
dc.rights	Copyright [2000]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subject	marine molluscs
dc.subject	chemical extraction
dc.subject	skin
dc.subject	mucus
dc.subject	metabolites
dc.subject	spectroscopic techniques
dc.subject	nuclear magnetic resonance
dc.subject	alkaloides
dc.subject	Jorunna funebris
dc.title	A new antitumor isoquinoline alkaloid from the marine nudibranch Jorunna funebris
dc.type	Journal Article