Renieramycins H and I, two novel alkaloids from the sponge Haliclona cribricutis Dendy

Abstract

The known alkaloid, mimosamycin 1, along with its moon- and di hydroxy derivaties, 4-hydroxy mimosamycin 2 and 1, 4-dihydroxymimosamycin 3 and two new dimeric alkaloids: namely renieramycins H and I 4 and 5 have been isolated from the MeOH extract of the bright blue sponge Haliclona cribricutis. These compounds have been purified on reverse phase HPLC and their structures finalized from their respective spectral data.