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    Biological investigations of Indian phaeophyceae. 15, effect of antibacterial substance extracted from Sargassum johnstionii Setchell et Gardner collected from Okha, west coast of India on the growth of bacteria

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    Seaweed_Res_Util_18_9.pdf (187.0Kb)
    Date
    1996
    Author
    Rao, P.P.S.
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    Abstract
    Cruide either extract and two fractions from the lipid namely fraction A (unsaponifiable) and fraction B (saponifiable) were obtained from a dry sample of Sargassum johnstionii. From these extracts different concentrations viz., 150 mu g, 200 mu g, 250 mu g and 300 mu g of extracts (added to 0.2ml solvent) were made and used per disc to test their efficiency to inhibit the growth of Staphylococcs aureus, S. albus, Bacillus magatherium (gram-positive), Proteus vulgaris, Escherichia coli and Psuedomonas aeruginosa (gram-negative). 250 mu g concentrations showed best antibacterial activity from all the extract. Highest antibacterials activity was exhibited by crude ether extract. Fraction B showed better activity than fraction A. Gram-positive bacteria were more sensitive to fractions as well as crule extracts than gram-negative bacteria. Highest antibacterial activity by crude ether extract was observed against Proteus vulgaris
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    http://drs.nio.org/drs/handle/2264/2155
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