Show simple item record

dc.contributor.authorReis-Henriques, M.A.
dc.contributor.authorFerreira, M.
dc.contributor.authorCoimbra, A.M.
dc.contributor.authorDeSilva, C.
dc.contributor.authorShailaja, M.S.
dc.date.accessioned2009-06-04T07:06:16Z
dc.date.available2009-06-04T07:06:16Z
dc.date.issued2009
dc.identifier.citationCiencias Marinas, vol.35(1); 29-40
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/3355
dc.description.abstractAquatic organisms may absorb organic compounds mainly from water and by ingestion of contaminated food. The toxicity of such compounds may be intensified by the presence of certain inorganic compounds such as nitrite (NO sub(2) sup(-)). In order to evaluate the effect of phenanthrene (PHE), a polycyclic aromatic hydrocarbon, in the presence and absence of NO sub(2) sup(-), juvenile sea bass, Dicentrarchus labrax L, were exposed to PHE i.p. and to NO sub(2) sup(-) in water, and several endpoints were measured at days 1, 3, and 6 of exposure. Sea bass exposed to PHE exhibited lower hepatic 7-ethoxyresorufin O-deethylase (EROD) activity as compared to the control group. The activity of the phase II enzyme, glutathione S-transferase (GST), was similar in all the groups of fish. The concentration of PHE metabolites, determined as fluorescent aromatic compounds, was nearly 14 times higher both in the presence and absence of NO sub(2) sup(-), showing that even at low EROD activities this PAH is metabolized. The presence of micronuclei was observed to be significantly higher only in sea bass treated with PHE alone, suggesting that different PHE metabolites, without genotoxic properties, were formed in the presence of NO sub(2) sup(-)
dc.language.isoen
dc.publisherUniversidad Autónoma de Baja California
dc.subjectmarine fish
dc.subjectpollution effects
dc.subjectbiomarkers
dc.subjectDicentrarchus labrax
dc.titlePhenanthrene and nitrite effects on juvenile sea bass, Dicentrarchus labrax, using hepatic biotransformation enzymes, biliary fluorescence, and micronuclei as biomarkers
dc.typeJournal Article


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record