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    Antifouling sesquiterpene from the Indian soft coral, Sinularia kavarattiensis Alderslade and Prita

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    Indian_J_Mar_Sci_39_270.pdf (98.99Kb)
    Date
    2010
    Author
    LimnaMol, V.P.
    Raveendran, T.V.
    Parameswaran, P.S.
    Kunnath, R.J.
    Sathyan, N.
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    Abstract
    A sesquiterpene, (1'E,5'E)-2-(2',6'-dimethylocta-1',5',7'-trienyl)-4-furoic acid [1], was isolated for the first time from the soft coral Sinularia kavarattiensis Alderslade & Prita collected from Gulf of Mannar (Tamil Nadu, India). This compound exhibited considerable larval settlement inhibition properties against the cosmopolitan biofouler, Balanus amphitrite. The observed mean EC sub(50) value of 11.21 mu g/ml is well within the biological potency cut off set for natural product antifoulants (NPA’s). The low EC sub(5) value and favourable therapeutic ratio (5.16) coupled with its known synthetic routes enhances the potential of 1 as a promising NPA
    URI
    http://drs.nio.org/drs/handle/2264/3684
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