Antioxidative potential of Perna viridis and its protective role against ROS induced lipidperoxidation and protein carbonyl

Abstract

The antioxidant potential of methanol extracts of green-lipped mussel (Perna viridis) were evaluated using tests such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, reducing potential, scavenging capacity of reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) and hydroxyl radical (OH•), and inhibition of lipid peroxidation (LPX) and protein carbonyl (PC). The scavenging activity of DPPH radical, H sub(2) O sub(2) and OH• radicals increased in dose dependent manner. The reducing power also increased significantly with increasing concentration but the effect was less sharp as compared to ascorbic acid as standard. Inhibition of LPX and PC levels shown by extract indicates its potential to protect the cell damage from ROS. Present investigation forms a first comprehensive report on the nutraceutical property of P. viridis