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    Calamenenes - aromatic bicyclic sesquiterpenes - from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786)

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    Nat_Prod_Res_25_169a.pdf (100.3Kb)
    Date
    2011
    Author
    LimnaMol, V.P.
    Raveendran, T.V.
    Naik, B.G.
    Kunnath, R.J.
    Parameswaran, P.S.
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    Abstract
    Three aromatic sesquiterpene derivatives, (+)-(7R, 10S)-2-methoxy calamenene (1), (+)-(7R, 10S)-2,5-dimethoxy calamenene (2) and (+)-(7R, 10S)-2-methoxy-5-acetoxy calamenene (3) were isolated from the methanol extract of the Indian gorgonian Subergorgia reticulata. Compound 2 has not been previously described in the literature. Compound 3 has not been isolated previously from a natural source. Compounds 1, 2 and 3 showed settlement inhibition activity against cyprids of Balanus amphitrite with EC sub (50) values of 4.4, 7.8 and 0.03 mu g mL sup(-1), respectively. These compounds also exhibited considerable activity against Artemia nauplii at 50 mu g mL sup(-1), indicative of their potential use as cytotoxic agents
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    http://drs.nio.org/drs/handle/2264/3781
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