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    (-)-6 alpha hydroxy polyanthellian A - A novel antifouling diterpenoid from the Indian soft coral Cladiella krempfi (Hickson)

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    Can_J_Chem_89_57a.pdf (200.3Kb)
    Date
    2011
    Author
    LimnaMol, V.P.
    Raveendran, T.V.
    Parameswaran, P.S.
    Kunnath, R.J.
    Rajamohanan, P.R.
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    Abstract
    Bioassay-guided purification of methanol extract of the soft coral Cladiella krempfi (Octocorallia: Alcynocea) yielded a novel eunicellin-type diterpenoid, (-)-6 alpha-hydroxy polyanthellin A (1), active against the cyprids of the fouling barnacle, Balanus amphitrite (EC sub(50) 9.02 mu g/mL; LC sub(50) 36 mg/mL; and therapeutic ratio = 4). The structure of compound 1 was determined from its spectral data, including IR, NMR (1D and 2D NMR), and mass spectra
    URI
    http://drs.nio.org/drs/handle/2264/3819
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