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dc.contributor.authorAl-Mourabit, A.
dc.contributor.authorZancanella, M.A.
dc.contributor.authorTilvi, S.
dc.contributor.authorRomo, D.
dc.date.accessioned2011-07-29T07:26:48Z
dc.date.available2011-07-29T07:26:48Z
dc.date.issued2011
dc.identifier.citationNatural Product Reports, vol.28(7); 2011; 1229-1260
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/3889
dc.description.abstractThe pyrrole-2-aminoimidazole (P-2-AI) alkaloids are a growing family of marine alkaloids, now numbering well over 150 members, with high topographical and biological information content. Their intriguing structural complexity, rich and compact stereochemical content, high N to C ratio (~1 : 2), and increasingly studied biological activities are attracting a growing number of researchers from numerous disciplines world-wide. This review surveys advances in this area with a focus on the structural diversity, biosynthetic hypotheses with increasing, but still rare, verifying experimental studies, asymmetric syntheses, and biological studies, including cellular target receptor isolation studies, of this stimulating and exciting alkaloid family
dc.language.isoen
dc.publisherThe Royal Society of Chemistry
dc.rightsAn edited version of this paper was published by and © The Royal Society of Chemistry 2011. http://dx.doi.org/10.1039/C0NP00013B
dc.subjectmarine alkaloids
dc.subjectasymmetric syntheses
dc.subjectstructural complexity
dc.titleBiosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids
dc.typeJournal Article


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