Isolation and x-ray structure of deoxycholic acid from the sponge Ircinia sp.

dc.contributor.author	Singh, K.S.
dc.contributor.author	Kaminsky, W.
dc.date.accessioned	2011-09-19T10:22:50Z
dc.date.available	2011-09-19T10:22:50Z
dc.date.issued	2011
dc.identifier.citation	Natural Product Communications, vol.6(9); 2011; 1237-1238
dc.identifier.uri	http://drs.nio.org/drs/handle/2264/3910
dc.description.abstract	Ethyl acetate extract of the sponge Ircinia sp., collected by SCUBA divers off the coast of southern India, contained a cholest-based sterol of insignificant antimicrobial activity, with one carboxylic acid side chain (3 Alpha, 7 Beta-dihydroxy-5 Beta-cholan-24-oic acid, DCA). The structure of the compound was determined by spectroscopic data and single crystal X-ray diffraction studies. DCA crystallizes in the tetragonal space group P4 sub(1) 2 sub(1) 2, chirality documented by solution optical rotation [Alpha] sub(D) =+67.4 degrees (c 0.16, CHCl sub(3)).
dc.language.iso	en
dc.publisher	Natural Product Communications Inc.
dc.rights	This is a preprint of an article published in [Natural Product Communications, vol.6(9); 2011; 1237-1238]”. Copyright © 2011 Natural Product Communications.
dc.subject	organic compounds
dc.subject	chemical extraction
dc.subject	x-ray diffraction analysis
dc.subject	esters
dc.title	Isolation and x-ray structure of deoxycholic acid from the sponge Ircinia sp.
dc.type	Journal Article