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    Vibrational spectroscopy for structural characterization of bioactive compounds

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    WW_Comphn_Anal_Chem_65_115a.pdf (678.1Kb)
    Date
    2014
    Author
    Singh, K.S.
    Majik, M.S.
    Tilvi, S.
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    Abstract
    Vibrational spectroscopy is one of the widely used analytical technique that require short analysis time, less sample quantity, provide non destructive and situ analysis of biological samples. Infrared and Raman spectroscopies have been used for the characterization of organic and inorganic compounds as well as natural products including macromolecules such as polysaccharides, proteins and highly insoluble melanin pigments. Although the techniques give less precise structural information, they are widely used for fast, nondestructive and green analysis, which is not possible to the other complementary techniques such as NMR and Mass. The technique coupled with NMR and mass can provide a strong platform for natural product analysis. This chapter presents the basic concepts of infrared and Raman spectroscopies and their application to the structure characterization of compounds such as polysaccharides, alkaloids, terpenes, flavonoids, sterols, sideorophores and isoluble melanin pigments isolated from marine organisms
    URI
    http://drs.nio.org/drs/handle/2264/4647
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