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dc.contributor.authorMazur-Marzec, H.
dc.contributor.authorBłaszczyk, A.
dc.contributor.authorFelczykowska, A.
dc.contributor.authorHohlfeld, N.
dc.contributor.authorKobos, J.
dc.contributor.authorToruńska-Sitarz, A.
dc.contributor.authorPrabhaDevi
dc.contributor.authorMontalva`o, S.
dc.contributor.authorDeSouza, L.
dc.contributor.authorTammela, P.
dc.contributor.authorMikosik, A.
dc.contributor.authorBloch, S.
dc.contributor.authorNejman-Faleńczyk, B.
dc.contributor.authorWęgrzyn, G.
dc.date.accessioned2015-11-02T07:21:04Z
dc.date.available2015-11-02T07:21:04Z
dc.date.issued2015
dc.identifier.citationEuropean Journal of Phycology, vol.50(3); 2015; 343-360
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/4842
dc.description.abstractCyanobacteria are effective producers of bioactive metabolites, including both acute toxins and potential pharmaceuticals. In the current work, the biological activity of 27 strains of Baltic cyanobacteria representing different taxonomic groups and chemotypes were tested in a wide variety of assays. The cyanobacteria showed strain-specific differences in the induced effects. The extracts from Nodularia spumigena CCNP1401 were active in the highest number of tests, including protease and phosphatase inhibition assays. Four strains from Nostocales and four from Oscillatoriales increased proliferation of mitogen-stimulated human T cells. In antimicrobial assays, Phormidium sp. CCNP1317 (Oscillatoriales) strongly inhibited the growth of six fouling Gammaproteobacteria. The growth of monocotyl Sorghum saccharatum was inhibited by both toxin-producing and ‘non-toxic’ strains. The Baltic cyanobacteria were also found to be a rich source of commercially important enzymes. Among the 19 enzymatic activities tested, alkaline phosphatase, acid phosphatase, esterase (C4 and C8), and naphthol-AS-BI-phosphohydrolase were particularly common. In the cyanobacterial extracts, different peptides which may have been responsible for the observed effects were identified using LC-MS/MS. Their structures were classified to microcystins, nodularins, anabaenopeptins, cyanopeptolins, aeruginosins, spumigins and nostocyclopeptides
dc.language.isoen
dc.publisherBritish Phycological Society
dc.rightsCopyright [2015] British Phycological Society. The final and definitive form of the preprint has been published in the "European Journal of Phycology" © 2015; "European Journal of Phycology" is available online at http://www.tandfonline.com with open URL of article : http://dx.doi.org/10.1080/09670262.2015.1062563. The term & condition associated with this preprint is at http://www.tandfonline.com/page/terms-and-conditions
dc.subjectMICROBIOLOGY::Physiology, biochemistry, biophysics
dc.subjectAQUATIC RESOURCES::Natural products
dc.subjectFOULING AND BORING::Prevention and control
dc.titleBaltic cyanobacteria- A source of biologically active compounds
dc.typeJournal Article


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