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dc.contributor.authorTilvi, S.
dc.contributor.authorSingh, K.S.
dc.date.accessioned2016-05-12T11:55:36Z
dc.date.available2016-05-12T11:55:36Z
dc.date.issued2016
dc.identifier.citationCurrent Organic Chemistry, vol.20(8); 2016; 898-929
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/4961
dc.description.abstractSecondary metabolites containing oxazole, oxazoline and isoxazoline ring skeletons are widely distributed in both marine and terrestrial organisms. They possess significant biological activities such as anti-tumor, antibacterial, anti-viral, anti-malarial and immunosuppressive. The complexity in the molecular structures coupled with their wide biological properties, has attracted the attention of many synthetic and natural product chemists. The introduction of multifunctional substituents and the construction of stereo-centers were considered as major challenges and obstacles in developing synthetic protocol for these classes of compounds. Few review articles on the total synthesis of oxazole contaning marine natural products namely bengazoles, phorboxazole, pseudopteroxazoles, hennoxazole and cyclopeptide have been reported till date. However, these reviews omitted the discussion on isolation and biological activities. In this review, we present the brief account on isolation, relevant biological activities and a recent development on the total synthesis of marine natural products containing oxazole, oxazoline and isoxazoline ring skeletons reported till 2014
dc.language.isoen
dc.publisherBentham Science Publishers
dc.rightsCopyright [2016]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subjectAQUATIC RESOURCES
dc.subjectAQUATIC ECOLOGY, PRODUCTIVITY
dc.subjectMICROBIOLOGY
dc.titleSynthesis of oxazole, oxazoline and isoxazoline derived marine natural products: A review
dc.typeJournal Article


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