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dc.contributor.authorKiran, K.
dc.contributor.authorAnas, A.
dc.contributor.authorSreelakshmi, P.K.
dc.contributor.authorSyamkumar, V.
dc.contributor.authorJasmin, C.
dc.contributor.authorPhilomina, B.
dc.contributor.authorKurien, Sobha
dc.date.accessioned2021-01-31
dc.date.accessioned2021-02-09T10:13:09Z
dc.date.available2021-01-11
dc.date.available2021-02-09T10:13:09Z
dc.date.issued2021
dc.identifier.citationProceedings, vol.66(1); 2021; Article no: 26
dc.identifier.issn2504-3900
dc.identifier.otherhttps://www.mdpi.com/2504-3900/66/1/26
dc.identifier.urihttps://doi.org/10.3390/proceedings2020066026
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/8363
dc.descriptionIF2019 - No Impact Factor
dc.description.abstractCholera outbreaks are prevalent in countries with a low Human Development Index (HDI) where people have limited access to safe drinking water, sanitation and hygiene (WASH). Intriguingly, the state of Kerala which records the highest HDI in India is endemic to cholera. We discuss the epidemiology of a cholera outbreak reported among migrant workers of Kerala in 2017. Virulence genes of Vibrio cholerae, toxR and ctxA, were detected in the river and ground water samples collected from the outbreaks sites which indicates need of enhanced awareness on WASH practices among migrant workers. The pathogenic Vibrio cholerae isolated from four patients in two districts had a similar DNA band pattern when analysed using repetitive extragenic palindromic-PCR (BOX), which indicates their single clonal origin. The four isolates were serotyped as O1 Ogawa. These isolates were resistant to multiple antibiotics including the carbapenem like imipenem. Nevertheless, isolates of these pathogenic bacteria were susceptible to tetracycline, identical to clinical isolates of Vibrio cholera reported earlier from this region. The current study highlights the importance of generating awareness on WASH protocols among migrant workers to prevent the outbreaks and considers community-based data as socioeconomic variable to predict the incidence of cholera.
dc.languageen
dc.publisherMultidisciplinary Digital Publishing Institute
dc.relation.ispartofMDPI Proc
dc.relation.isreferencedbyNON-SCI
dc.rightsOnly the author version of the copright reserved papers uploaded. Contact drs@nio.org for any complaints regarding copyright violations
dc.titleMultiple Drug-Resistant Vibrio Cholerae Responsible for Cholera Outbreak among Migrant Domestic Workers in Kerala, South India
dc.typeJournal Article
dc.affiliation.authorCSIR-National Institute of Oceanography, Kochi, Kerala, India


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