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dc.contributor.authorRamesh, Ch.
dc.contributor.authorTulasi, B.R.
dc.contributor.authorRaju, M.
dc.contributor.authorThakur, N.
dc.contributor.authorDufosse, L.
dc.date.accessioned2021-06-16
dc.date.accessioned2021-06-22T10:09:07Z
dc.date.available2021-05-26
dc.date.available2021-06-22T10:09:07Z
dc.date.issued2021
dc.identifier.citationMarine Drugs, vol.19(6); 2021; Article no: 308
dc.identifier.issn1660-3397
dc.identifier.otherhttps://www.mdpi.com/1660-3397/19/6/308
dc.identifier.urihttps://doi.org/10.3390/md19060308
dc.identifier.urihttps://drs-beta.nio.org/drs/handle/2264/8678
dc.descriptionIF2019 - 4.073
dc.description.abstractMarine tunicates are identified as a potential source of marine natural products (MNPs), demonstrating a wide range of biological properties, like antimicrobial and anticancer activities. The symbiotic relationship between tunicates and specific microbial groups has revealed the acquisition of microbial compounds by tunicates for defensive purpose. For instance, yellow pigmented compounds, �tambjamines�, produced by the tunicate, Sigillina signifera (Sluiter, 1909), primarily originated from their bacterial symbionts, which are involved in their chemical defense function, indicating the ecological role of symbiotic microbial association with tunicates. This review has garnered comprehensive literature on MNPs produced by tunicates and their symbiotic microbionts. Various sections covered in this review include tunicates� ecological functions, biological activities, such as antimicrobial, antitumor, and anticancer activities, metabolic origins, utilization of invasive tunicates, and research gaps. Apart from the literature content, 20 different chemical databases were explored to identify tunicates-derived MNPs. In addition, the management and exploitation of tunicate resources in the global oceans are detailed for their ecological and biotechnological implications
dc.languageen
dc.publisherMultidisciplinary Digital Publishing Institute
dc.relation.isreferencedbySCI
dc.rightsOnly the author version of the copright reserved papers uploaded. Contact drs@nio.org for any complaints regarding copyright violations
dc.titleMarine Natural Products from Tunicates and their associated microbes
dc.typeJournal Article
dc.affiliation.authorCSIR-National Institute of Oceanography, Dona Paula, Goa, India


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