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    Convenient synthesis of volatile streptomyces lactones

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    Synthesis_14_2341.pdf (74.60Kb)
    Date
    2005
    Author
    Amonkar, C.P.
    Tilve, S.G.
    Parameswaran, P.S.
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    Abstract
    A convenient three-step synthetic approach towards 3-alkyl-5-methyl-2[5H]furanones is described. The steps involved in the synthesis are domino primary alcohol oxidation-Wittig reaction, acid-catalysed lactonisation and isomerisation. This synthetic approach has been exploited to synthesise four Streptomyces lac-tones.
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    http://drs.nio.org/drs/handle/2264/887
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