Convenient synthesis of volatile streptomyces lactones
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Date
2005Author
Amonkar, C.P.
Tilve, S.G.
Parameswaran, P.S.
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A convenient three-step synthetic approach towards 3-alkyl-5-methyl-2[5H]furanones is described. The steps involved in the synthesis are domino primary alcohol oxidation-Wittig reaction, acid-catalysed lactonisation and isomerisation. This synthetic approach has been exploited to synthesise four Streptomyces lac-tones.
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