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    Naturally Fluorescent Field Mouse, Mus booduga (Gray, 1837) and Common House Gecko, Hemidactylus frenatus (Schlegel, 1836) as Model Organisms for Biomedical Studies

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    Date
    2022
    Author
    Ramesh, Ch.
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    Abstract
    Since the discovery of the Green fluorescent protein from crystal jellyfish Aequorea victoria, many fluorescent organisms have been identified from different parts of the world.As a result, various fluorescent proteins such as GFP, RFP, and DsRed are discovered and widely used in genetic engineering studies to label a wide range of proteins and genes in mouse models.In bioimaging research, a variety of mouse models are used to visualize fluorescence-based phenotypic variations.In this study, the field mouse, Mus booduga, and common house gecko Hemidactylus frenatus dispalyed natural blue fluorescence (440-480~nm).The fur of M.booduga and bones of H.frenatus have displayed blue fluorescence.These organisms may serve as a naturally fluorescent models in bioimaging studies to study phenotypic changes triggered by physico-chemical factors.This study infers that implication of fluorescent terrestrial chordates in evolutionary studies would delineate the origins (ocean to land) and phylogenetic pathways of fluorescent trait in eukaryotes.
    URI
    https://doi.org/10.1007/S40009-022-01138-2/METRICS
    https://drs.nio.org/drs/handle/2264/8949
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