• Login
    View Item 
    •   DSpace Home
    • Institute's contributions
    • Scholarly literature
    • View Item
    •   DSpace Home
    • Institute's contributions
    • Scholarly literature
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Unveiling the Toxic Impact and Biodegradation Products of Anionic Surfactants in an Edible Clam Meretrix casta Through Tandem Mass Spectrometry

    Thumbnail
    Author
    Fernandes, C.
    Wahidullah, S.
    Dahihande, A.S.
    Tilvi, S.
    Metadata
    Show full item record
    Abstract
    Shellfish, being filter feeders, are susceptible to bioaccumulating environmental contaminants. This study examines the occurrence, bioaccumulation, and in vivo transformation of linear alkylbenzene sulfonates (C10–C13 LAS) and their degradation products, sulfophenyl carboxylic acids (C10–C11 SPCs), in the edible clam Meretrix casta from the estuary of Goa, India. Using electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF MS/MS), diagnostic fragment ions formed enabled detection and structural characterization of LAS and their biodegradation intermediates in clams under natural conditions. Acute toxicity assays revealed 100% lethality of commercial LAS at 3.5 mg/L, with an LC50 of 2.67 mg/L. Laboratory exposure experiments demonstrated in vivo biotransformation of LAS into oxidized saturated and unsaturated biodegraded products, SPCs, and dicarboxylates (SPdCs) with carbon chains of C4, C6, C8, C10, and C12 for C12LAS and methylated C13SPdCs for C13LAS. This was confirmed by fragment ions analysis using ESI-triple quadrupole (TQ) MS/MS. The study provides the first direct evidence of detailed tandem mass spectrometric data used for characterizing the structure of LAS biodegraded products. These compounds hold potential as biomarkers for pollutant exposure. Their MS-based metabolite detection with the proposed biodegradation pathway can be applied for environmental monitoring and ecological risk assessment. The investigation reveals its metabolic capacity to transform and detoxify, contributing to our understanding of bivalve biotransformation mechanisms and their role in pollutant cycling in coastal ecosystems.
    URI
    https://doi.org/10.1002/slct.202504478
    http://drs.nio.res.in/drs/handle/2264/9587
    Collections
    • Scholarly literature [9223]

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV