dc.contributor.author | Shailaja, M.S. | |
dc.contributor.author | Rajamanickam, R. | |
dc.contributor.author | Wahidullah, S. | |
dc.date.accessioned | 2006-06-12T05:56:23Z | |
dc.date.available | 2006-06-12T05:56:23Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Environmental Pollution, vol.143(1), 174-177 | |
dc.identifier.uri | http://drs.nio.org/drs/handle/2264/112 | |
dc.description.abstract | Nitrite (NO2−), a highly reactive chemical species, accumulates in coastal waters as a result of pollution with nitrogenous waste and/or an imbalance in the bacterial processes of nitrification and denitrification. The present study probed the impact of nitrite (NO2−) on the metabolism of polycyclic aromatic hydrocarbons (PAHs) in fish. In a laboratory experiment, exposure of euryhaline fish, Oreochromis mossambicus to industrial effluents containing PAHs in the presence of NO2− enhanced the cytochrome P450-dependent biotransformation activity determined as 7-ethoxyresorufin-O-deethylase (EROD), by nearly 36% compared to the value observed in the absence of NO2− (50.2 ± 6.74 pmol resorufin min−1 g−1 liver). Fixed wavelength fluorescence measurements in bile revealed maximum enhancement to have occurred in the metabolites of benzo[a]pyrene, a carcinogenic PAH. Lasting, sublethal physiological deterioration was apparent in fish exposed simultaneously to an oil refinery effluent and NO2−, from the unremittingly decreasing liver somatic index, even after the withdrawal of the contaminants. | |
dc.format.extent | 280281 bytes | |
dc.format.mimetype | application/pdf | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.rights | Copyright © 2005 Elsevier Ltd All rights reserved | |
dc.subject | Coastal waters | |
dc.subject | Bile metabolites | |
dc.subject | Benzo[a]pyrene | |
dc.subject | Polycyclic aromatic hydrocarbon (PAH) | |
dc.subject | Nitrite | |
dc.title | Increased formation of carcinogenic PAH metabolites in fish promoted by nitrite | |
dc.type | Journal Article | |