Show simple item record

dc.contributor.authorShailaja, M.S.
dc.contributor.authorRajamanickam, R.
dc.contributor.authorWahidullah, S.
dc.date.accessioned2006-06-12T05:56:23Z
dc.date.available2006-06-12T05:56:23Z
dc.date.issued2006
dc.identifier.citationEnvironmental Pollution, vol.143(1), 174-177
dc.identifier.urihttp://drs.nio.org/drs/handle/2264/112
dc.description.abstractNitrite (NO2−), a highly reactive chemical species, accumulates in coastal waters as a result of pollution with nitrogenous waste and/or an imbalance in the bacterial processes of nitrification and denitrification. The present study probed the impact of nitrite (NO2−) on the metabolism of polycyclic aromatic hydrocarbons (PAHs) in fish. In a laboratory experiment, exposure of euryhaline fish, Oreochromis mossambicus to industrial effluents containing PAHs in the presence of NO2− enhanced the cytochrome P450-dependent biotransformation activity determined as 7-ethoxyresorufin-O-deethylase (EROD), by nearly 36% compared to the value observed in the absence of NO2− (50.2 ± 6.74 pmol resorufin min−1 g−1 liver). Fixed wavelength fluorescence measurements in bile revealed maximum enhancement to have occurred in the metabolites of benzo[a]pyrene, a carcinogenic PAH. Lasting, sublethal physiological deterioration was apparent in fish exposed simultaneously to an oil refinery effluent and NO2−, from the unremittingly decreasing liver somatic index, even after the withdrawal of the contaminants.
dc.format.extent280281 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherElsevier
dc.rightsCopyright © 2005 Elsevier Ltd All rights reserved
dc.subjectCoastal waters
dc.subjectBile metabolites
dc.subjectBenzo[a]pyrene
dc.subjectPolycyclic aromatic hydrocarbon (PAH)
dc.subjectNitrite
dc.titleIncreased formation of carcinogenic PAH metabolites in fish promoted by nitrite
dc.typeJournal Article


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record