Antispasmodic action of 5-methyl benzoxazoline-2-one: A preliminary study

dc.contributor.author	DeSouza, R.D.
dc.contributor.author	Bhandare, P.N.
dc.contributor.author	Fernandes, N.
dc.contributor.author	Wahidullah, S.
dc.contributor.author	DeSouza, L.
dc.date.accessioned	2009-01-12T08:56:38Z
dc.date.available	2009-01-12T08:56:38Z
dc.date.issued	1997
dc.identifier.citation	Indian Journal of Pharmacology, Vol.29; 327-328p.
dc.identifier.uri	http://drs.nio.org/drs/handle/2264/2013
dc.description.abstract	In the present study, compound (1) depressed both phases of the dose-response curve. The marked effect on 5-HT response cannot be attributed solely to an antimuscarinic action of the compound which was much less (66%) as compared to (88%) in the case of 5-HT. The varying inhibitory effect of the compound of different spasmogens acting via diverse mechanisms suggests that its locus of action may be at a post receptor site, at some step in the transduction pathway. Further work is needed to elucidate the exact mode of action of this compound
dc.language.iso	en
dc.publisher	Indian Pharmacological Society
dc.rights	Copyright [1997]. All efforts have been made to respect the copyright to the best of our knowledge. Inadvertent omissions, if brought to our notice, stand for correction and withdrawal of document from this repository.
dc.subject	bioactiv compounds
dc.subject	drugs
dc.subject	screening
dc.title	Antispasmodic action of 5-methyl benzoxazoline-2-one: A preliminary study
dc.type	Journal Article