• Login
    View Item 
    •   DSpace Home
    • Institute's contributions
    • Scholarly literature
    • View Item
    •   DSpace Home
    • Institute's contributions
    • Scholarly literature
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Molecular Biomarkers: Their significance and application in marine pollution monitoring

    Thumbnail
    View/Open
    Ecotoxicology_15_333.pdf (185.4Kb)
    Date
    2006
    Author
    Sarkar, A.
    Ray, D.
    Shrivastava, A.N.
    Sarkar, S.
    Metadata
    Show full item record
    Abstract
    This paper presents an overview of the significance of the use of molecular biomarkers as diagnostic and prognostic tools for marine pollution monitoring. In order to assess the impact of highly persistent pollutants such as polychlorinated biphenyls (PCB), polychlorinated dibenzo-dioxins (PCDD), polychlorinated dibenzo-furans (PCDF), polynuclear aromatic hydrocarbons (PAH), tributyltin (TBT) and other toxic metals on the marine ecosystem a suite of biomarkers are being extensively used worldwide. Among the various types of biomarkers, the following have received special attention: cytochrome P4501A induction, DNA integrity, acetylcholinesterase activity and metallothionein induction. These biomarkers are being used to evaluate exposure of various species of sentinel marine organisms (e.g. mussels, clams, oysters, snails, fishes, etc.) to and the effect of various contaminants (organic xenobiotics and metals) using different molecular approaches. The induction of the biotransformation enzyme, cytochrome P4501A in fishes (Callionymus lyra, Limanda limanda, Serranus sp., Mullus barbatus) and mussels (Dreissena polymorpha) by various xenobiotic contaminants such as PCBs, PAHs, PCDs is used as a biomarker of exposure to such organic pollutants. In order to assess the impact of neurotoxic compounds on marine environment the evaluation of acetylcholinesterase activity in marine organisms is used as a biomarker of exposure to neurotoxic agents such as organophosphorus, carbamate pesticides etc. Metallothioneins (MTs) are induced by toxic metals such as Cd, Hg, and Cu by chelation through cysteine residues and are used in both vertebrates and invertebrates as a biomarker of metal exposure. The measurement of the levels of DNA integrity in marine organisms such as Sea stars (Asterias rubens) from the North Sea and the marine snails (Planaxis sulcatus) from the Arabian Sea along the Goa coast exposed to environmental xenobiotic contaminants clearly indicated the extent and the nature of pollution at the sampling sites along coastal environment.
    URI
    http://drs.nio.org/drs/handle/2264/853
    Collections
    • Scholarly literature [9127]

    Related items

    Showing items related by title, author, creator and subject.

    • Marine pollution - What are we heading for? 

      Zingde, M.D. (Indian National Science Academy, New Delhi (India), 1999)
      Unlike the open ocean, the coastal zone is the most affected and vulnerable to human abuse with several nearshore areas including well-flushed regions and enclosed and semi-enclosed seas getting increasingly polluted. This ...
    • Detection of pollutants in marine organisms and in the environment as markers of environmental quality 

      Sarkar, A. (Pennsilvania Academy of Science, 2005)
      This chapter presents an overview of various techniques of detection of different types of pollutants such as organochlorine pesticides (e.g. DDT, HCHs, aldrin, dieldrin, endrin, Hepox, heptaclor), polychlorinated biphenyls ...
    • Dispersion processes in coastal waters - Some outstanding practical issues for monitoring and modelling 

      Swamy, G.N. (Indian Inst. of Technol., New Delhi and NIO, India, 1994)
      This paper highlights on the issues of dispersion processes in coastal waters like space-time description of field parameters, limitation of physical models, limitations of numerical formulations, Eulerian-Lagrangian ...

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV