Now showing items 21-25 of 25

    • Synthesis of (R)-norbgugaine and its potential as quorum sensing inhibitor against Pseudomonas aeruginosa 

      Majik, M.S.; Naik, D.; Bhat, C.; Tilve, S.; Tilvi, S.; DeSouza, L. (Elsevier, 2013)
      (R)-Bgugaine is a natural pyrrolidine alkaloid from Arisarum vulgare, which shows antifungal and antibacterial activity. We have accomplished the simple synthesis of norbgugaine (demethylated form of natural bgugaine) ...
    • Tandem Wittig-ene reaction approach to kainic acid 

      Majik, M.S.; Parameswaran, P.S.; Tilve, S.G. (American Chemical Society, 2009)
      The first example of a tandem Wittig-intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic pathway involves conversion of prenyl bromide into phosphorane ...
    • Total synthesis of (-)- and (+)-tedanalactam 

      Majik, M.S.; Parameswaran, P.S.; Tilve, S.G. (American Chemical Society, 2009)
      The first stereoselective route providing access to both enantiomers of tedanalactam, a naturally occurring piperidone, has been developed. The stereogenic centers were generated by the use of Sharpless asymmetric ...
    • Vibrational spectroscopy for structural characterization of bioactive compounds 

      Singh, K.S.; Majik, M.S.; Tilvi, S. (Elsevier, 2014)
      Vibrational spectroscopy is one of the widely used analytical technique that require short analysis time, less sample quantity, provide non destructive and situ analysis of biological samples. Infrared and Raman spectroscopies ...
    • γ-Hydroxybutenolide Containing Marine Natural Products and Their Synthesis: A Review 

      Tilvi, S.; Khan, Safia; Majik, M.S. (Bentham Science Publishers Ltd., 2019)
      Gamma-Hydroxybutenolides (gamma-HB) is an important structural core found in many bioactive marine natural products (MNPS). The gamma-HB core containing NPS served as an inspiration to medicinal chemists to undertake ...